منابع مشابه
Pooling in chronic orthostatic intolerance: arterial vasoconstrictive but not venous compliance defects.
BACKGROUND Orthostatic intolerance is characterized by postural tachycardia syndrome (POTS) with exaggerated tachycardia, orthostatic symptoms, and "pooling" (which comprises acrocyanosis and dependent edema when upright). My colleagues and I tested the hypothesis that pooling results from increased venous compliance in POTS patients. METHODS AND RESULTS Fifteen patients aged 13 to 19 years w...
متن کاملNeurocirculatory abnormalities in chronic orthostatic intolerance.
BACKGROUND Chronic orthostatic intolerance (COI) occurs in postural tachycardia syndrome (POTS) and in some individuals with repeated neurocardiogenic syncope/presyncope (NCS), without POTS. This study addressed whether patients with COI and POTS or NCS have neurocirculatory abnormalities during supine rest. METHODS AND RESULTS Adult patients referred for COI who had POTS (n=90, mean+/-SEM ag...
متن کاملCardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
BACKGROUND In postural tachycardia syndrome (POTS) and repeated neurocardiogenic presyncope (NCS), orthostatic intolerance occurs without persistent sympathetic neurocirculatory failure. Whether these conditions involve abnormal cardiac sympathetic innervation or function has been unclear. METHODS AND RESULTS Patients with POTS or NCS underwent measurements of neurochemical indices of cardiac...
متن کاملVascular perturbations in the chronic orthostatic intolerance of the postural orthostatic tachycardia syndrome.
Chronic orthostatic intolerance is often related to the postural orthostatic tachycardia syndrome (POTS). POTS is characterized by upright tachycardia. Understanding of its pathophysiology remains incomplete, but edema and acrocyanosis of the lower extremities occur frequently. To determine how arterial and venous vascular properties account for these findings, we compared 13 patients aged 13-1...
متن کاملChronic orthostatic intolerance: part of a spectrum of dysfunction in orthostatic cardiovascular homeostasis?
Chronic orthostatic intolerance (COI, also known as postural orthostatic tachycardia syndrome) is a disorder that most frequently affects young women (female-to-male ratio, 4:1). Presenting symptoms include lightheadedness, palpitations, fatigue, blurred vision, dizziness, exercise intolerance, chest discomfort, cognitive impairment, and occasionally syncope. These symptoms usually occur after ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000016348.55378.c4